CHRND Polyclonal Antibody

Catalog Number:

27449

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q07001
NCBI Gene ID:1144

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human CHRND (NP_000742.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF