UNC13D Polyclonal Antibody

Catalog Number:

27917

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q70J99
NCBI Gene ID:201294

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human UNC13D (NP_954712.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

References:

appl_detail:

WB 1:1000 - 1:2000

Datasheet PDF