NKX2-6 Antibody

Catalog Number:

25432

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:A6NCS4
Gene ID:137814

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the center of human NKX2-6.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms

Applications:

ELISA WB

Background:

NKX2-6 (NK2 homeobox 6) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-6 is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are thought to be a cause for some congenital heart abnormalities.

References:

appl_detail:

Datasheet PDF