ANGPT2 Antibody

Catalog Number:

25428

Amount:

100μg

Price:

$319

Swiss-Prot No:

P_001138

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the carboxy terminus of human ANGPT2.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms.

Applications:

ELISA WB

Background:

Angiopoietin-2 (ANGPT2) is a member of the Ang family, a family of angiogenic factors that play major roles in angiogenesis during the development and growth of human cancers, but also during lymphangiogenesis. ANGPT2 is generally considered an antagonist of ANGPT1 and endothelial TEK tyrosine kinase (TIE-2, TEK). ANGPT2 disrupts the vascular remodeling ability of ANGPT1 and is thought to induce endothelial cell apoptosis, resulting in vessel regression. Expression of ANGPT2 has been linked to invasive and metastatic phenotypes of gliomas and other cancers .

References:

appl_detail:

Datasheet PDF