MLIP Antibody

Catalog Number:

25425

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5VWP3
Gene ID:90523

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide near the carboxy terminus of human MLIP.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of MLIP are known to exist.

Applications:

ELISA WB

Background:

The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies

References:

appl_detail:

Datasheet PDF