GBP6 Antibody

Catalog Number:

25422

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q6ZN66
Gene ID:163351

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the carboxy terminus of human GBP6.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

GBP6 antibody is predicted to not cross-react with other GBP family members.

Applications:

ELISA WB

Background:

The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation .

References:

appl_detail:

Datasheet PDF