LEMD3 Antibody

Catalog Number:

25389

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y2U8
Gene ID:23592

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the carboxy terminus of human LEMD3.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2

Applications:

ELISA WB

Background:

LEMD3 (LEM domain-containing 3) is a lem-domain containing protein, also known as MAN1, whose loss of function results in disorders characterized by osteopoikilosis, Buschke-Ollendorff syndrome, and melorheostosis. LEMD3 is an inner nuclear membrane protein that interacts with BMP and activin-TGF-beta receptor-activated Smads and antagonizes TGF-beta signaling in human cells.

References:

appl_detail:

Datasheet PDF