TGM5 Antibody

Catalog Number:

25370

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O43548
Gene ID:9333

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the carboxy terminus of human TGM5.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

TGM5 antibody is predicted to not cross-react with other TGase protein family members. Multiple isoforms of TGM5 are known to exist.

Applications:

ELISA WB

Background:

Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies. TGM5 is also expressed in the human hair follicle. Defects in TGM5 are associated with acral peeling skin syndrome.

References:

appl_detail:

Datasheet PDF