CCDC55 Antibody

Catalog Number:

25366

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9H0G5
Gene ID:84081

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide near the carboxy terminus of human CCDC55.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms are known to exist; this antibody will detect all three.

Applications:

ELISA WB

Background:

CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.

References:

appl_detail:

Datasheet PDF