HIG1 Antibody

Catalog Number:

25357

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y241
Gene ID:25994

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the amino terminus of human HIG1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

HIG1 antibody is predicted to not cross-react with HIG2

Applications:

ELISA WB

Background:

HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG1 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.

References:

appl_detail:

Datasheet PDF