Paralemmin3 Antibody

Catalog Number:

25344

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:A6NDB9
Gene ID:342979

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the amino terminus of human Paralemmin3.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform

Applications:

ELISA WB

Background:

Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.

References:

appl_detail:

Datasheet PDF