SIK1 Antibody

Catalog Number:

25301

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P57059
Gene ID:102724428

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the center of human SIK1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Two isoforms of SIK1 are known to exist; this antibody will detect both isoforms. SIK1 antibody is predicted to not cross-react with other SIK protein family members.

Applications:

ELISA WB

Background:

Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.

References:

appl_detail:

Datasheet PDF