ROCK2 Antibody

Catalog Number:

25300

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O75116
Gene ID:9475

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the center of human ROCK2.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Three isoforms of ROCK2 are known to exist; this antibody recognizes all three isoforms. ROCK2 antibody is predicted to not cross-react with other ROCK protein family members.

Applications:

ELISA WB

Background:

ROCK2 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK2 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK2, like its isozyme ROCK1, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.

References:

appl_detail:

Datasheet PDF