ROCK1 Antibody

Catalog Number:

25299

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q13464
Gene ID:6093

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the amino terminus of human ROCK1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

ROCK1 antibody is predicted to not cross-react with other ROCK protein family members.

Applications:

ELISA WB

Background:

ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.

References:

appl_detail:

Datasheet PDF