RABEX5 Antibody

Catalog Number:

25276

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UJ41
Gene ID:27342

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the center terminus of human RABEX5.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.

Applications:

ELISA WB

Background:

RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.

References:

appl_detail:

Datasheet PDF