MYOZAP Antibody

Catalog Number:

25275

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P0CAP1
Gene ID:100820829

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 18 amino acid peptide near the carboxy terminus of human MYOZAP.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Multiple isoforms of MYOZAP are known to exist.

Applications:

ELISA WB

Background:

MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.

References:

appl_detail:

Datasheet PDF