VPS39 Antibody

Catalog Number:

25263

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96JC1
Gene ID:23339

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 18 amino acid peptide near the carboxy terminus of human VPS39.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least four isoforms of VPS39 are known to exist; this antibody will detect all four. VPS39 antibody is predicted not to cross-react with TRAP1.

Applications:

ELISA WB IHC

Background:

VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.

References:

appl_detail:

Datasheet PDF