1-832-868-1888
order@swbio.com

Catalog Number: |
25260 |
| other_names: | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, Termination and polyadenylation 1 homolog, TPA1 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q8N543 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
|
Immunogen: |
Raised against a 18 amino acid peptide near the carboxy terminus of human OGFOD1. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist; this antibody will only detect the larger isform. |
Applications: |
ELISA WB |
Background: |
OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells. |
References: |
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appl_detail: |
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