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OGFOD1 Antibody

Catalog Number:

25260
other_names: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, Termination and polyadenylation 1 homolog, TPA1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8N543
Gene ID:55239

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 18 amino acid peptide near the carboxy terminus of human OGFOD1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist; this antibody will only detect the larger isform.

Applications:

ELISA WB

Background:

OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.

References:

appl_detail:

Datasheet PDF

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