1-832-868-1888
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Catalog Number: |
25251 |
| other_names: | Zinc finger MYM-type protein 3, ZNF261, ZNF198L2, XFIM, MYM |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q14202 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
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Immunogen: |
Raised against a 20 amino acid peptide near the carboxy terminus of human AXIN2. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
At least three isoforms of ZMYM3 are known to exist; this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members. |
Applications: |
ELISA WB |
Background: |
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. |
References: |
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appl_detail: |
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