1-832-868-1888
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Catalog Number: |
25364 |
| other_names: | FCH and double SH3 domains protein 1, NWK2 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q86WN1 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
|
Immunogen: |
Raised against a 15 amino acid peptide near the carboxy terminus of human FCHSD1. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
Multiple isoforms of FCHSD1 are known to exist. FCHSD1 antibody is predicted to not cross-react with FCHSD2 |
Applications: |
ELISA WB |
Background: |
The FCH and double SH3 domains protein 1 (FCHSD1, also known as NWK2) and the related protein FCHSD2 were initially identified in silico as distantly related proteins to FNBP1 and FNBP2. Both share the common domain structure consisting of FCH, FBH, two SH3 and C-terminal proline-rich domains. While little is known of the function of FCHSD1, the related protein NWK is an adaptor protein that is thought to regulate Rho activity downstream of Robo receptors, suggesting that FCHSD1 may be involved in synaptic morphology by regulating actin dynamics in presynaptic terminals. |
References: |
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appl_detail: |
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