SGK1 Antibody

Catalog Number:

25309

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O00141
Gene ID:6446

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the carboxy terminus of human SGK1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

SGK1 antibody is predicted to not cross-react with other SGK protein family members. At least five isoforms are known to exist

Applications:

ELISA WB

Background:

Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

References:

appl_detail:

Datasheet PDF