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INCA1 Antibody

Catalog Number:

25023
other_names: Inhibitor of CDK1 interacting with cyclin A1, HSD45

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96EL1
Gene ID:389119

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide from near the carboxy terminus of human INCA1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Applications:

ELISA WB

Background:

INCA1 was isolated through a yeast triple hybrid approach to identify interaction partners of the cyclin A1-CDK2 heterodimer. INCA1 is evolutionarily conserved and has no homology to any known proteins. Like Cyclin A1, INCA1 is highly expressed in testis with highest levels observed at various points of testis maturation. It has been suggested that the complex of INCA1 and the cyclinA1-CDK2 dimer plays a role in several signaling pathways important for cell cycle control and meiosis. Recent experiments have shown that INCA1 also interacts with the testis protein RSB-66 and this interaction takes place in the cytoplasm.

References:

appl_detail:

Datasheet PDF

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