PGCC1 Antibody

Catalog Number:

24951

Amount:

100μg

Price:

$319

Swiss-Prot No:

Q96EK7

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide from near the carboxy terminus of human PGCC1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

This antibody will not cross-react with FAM120A.

Applications:

ELISA WB

Background:

The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.

References:

appl_detail:

Datasheet PDF