ZBED3 Antibody

Catalog Number:

24874

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96IU2
Gene ID:84327

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide from near the amino terminus of human ZBED3.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

Applications:

ELISA WB

Background:

Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.

References:

appl_detail:

Datasheet PDF