MettL7B Antibody

Catalog Number:

24786

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q6UX53
Gene ID:196410

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide near the carboxy terminus of human MettL7B.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

This MettL7B antibody is predicted to not cross-react with MettL7A.

Applications:

ELISA WB IHC

Background:

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

References:

appl_detail:

Datasheet PDF