GRTP1 Antibody

Catalog Number:

24677

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5TC63
Gene ID:79774

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide from near the center of human GRTP1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.

Applications:

ELISA WB

Background:

Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.

References:

appl_detail:

Datasheet PDF