Coagulation factor III/Tissue Factor Rabbit mAb

Catalog Number:

78902

Amount:

100μg

Price:

$318

Swiss-Prot No:

P13726

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Coagulation factor III/Coagulation factor III/Tissue Factor

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF