Caldesmon Rabbit mAb

Catalog Number:

78899

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q05682

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Caldesmon

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF