Complement factor H Rabbit mAb

Catalog Number:

78897

Amount:

100μg

Price:

$318

Swiss-Prot No:

P08603

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Complement factor H

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF