1-832-868-1888
order@swbio.com
Catalog Number: |
78882 |
other_names: | PCNA;ATLD2 |
Amount: |
100μg |
calculated_mw: | 28kDa |
host_species: | Mouse |
Price: |
$318 |
Swiss-Prot No: |
P12004 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
Recombinant protein of human PCNA |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC |
Background: |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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