IRF4 Rabbit mAb

Catalog Number:

78878

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q15306

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human IRF4

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF