Phospho-TAK1-S439 Rabbit mAb

Catalog Number:

78875

Amount:

100μg

Price:

$318

Swiss-Prot No:

O43318

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Phospho-TAK1 (S439).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF