GluR4/GluA4/GRIA4 Rabbit mAb

Catalog Number:

78860

Amount:

100μg

Price:

$318

Swiss-Prot No:

P48058

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human GluR4/GluA4/GRIA4

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF