CDKN1C/p57 Kip2 Rabbit mAb

Catalog Number:

78845

Amount:

100μg

Price:

$318

Swiss-Prot No:

P49918

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CDKN1C/p57 Kip2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF