POLR2A Rabbit mAb

Catalog Number:

78811

Amount:

100μg

Price:

$318

Swiss-Prot No:

P24928

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human POLR2A.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF