AT1R/AGTR1 Rabbit mAb

Catalog Number:

78808

Amount:

100μg

Price:

$318

Swiss-Prot No:

P30556

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human AT1R/AGTR1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF