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Home > products > Phospho-ERK1-T202 + ERK2-T185 Rabbit mAb

Phospho-ERK1-T202 + ERK2-T185 Rabbit mAb

Catalog Number:

78761
other_names: H3.4;H3/g;H3FT;H3t;H3/A;H3FA;ERK1 / ERK2

Amount:

100μg
calculated_mw: 42,44kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

P28482/P27361

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Phospho-ERK1 (T202) + ERK2 (T185).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

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