alpha + beta Synuclein Rabbit mAb

Catalog Number:

78754

Amount:

100μg

Price:

$318

Swiss-Prot No:

P37840/Q16143

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human alpha + beta Synuclein

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF