ERAB/HSD17B10 Rabbit mAb

Catalog Number:

78732

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q99714

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human ERAB/HSD17B10

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF