MonoMethyl-Histone H3-R2 Rabbit mAb

Catalog Number:

78729

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q16695/P68431

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Histone H3 (mono methyl R2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,ChIP

Background:

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

References:

appl_detail:

WB 1:500 - 1:2000
ChIP 1:20 - 1:100

Datasheet PDF