Glypican 3 (GPC3) Rabbit mAb

Catalog Number:

78674

Amount:

100μg

Price:

$318

Swiss-Prot No:

P51654

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Glypican 3 (GPC3) (GPC3)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF