Integrin alpha 4 (ITGA4/CD49d) Rabbit mAb

Catalog Number:

78668

Amount:

100μg

Price:

$318

Swiss-Prot No:

P13612

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Integrin alpha 4 (ITGA4/CD49d) (ITGA4/CD49d)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF