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Catalog Number: |
78663 |
other_names: | CD51;MSK8;VNRA;VTNR;Integrin alpha V;ITGAV |
Amount: |
100μg |
calculated_mw: | 125kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P06756 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human Integrin alpha V (ITGAV/CD51) (ITGAV/CD51) |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC |
Background: |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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