ESRα Rabbit mAb

Catalog Number:

78627

Amount:

100μg

Price:

$318

Swiss-Prot No:

P03372

Form of Antibody:

Storage/Stability:

Immunogen:

A synthetic peptide of human Estrogen Receptor alpha (ESRα)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

References:

appl_detail:

WB 1:1000 - 1:2000
IF 1:50 - 1:200

Datasheet PDF