1-832-868-1888
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Catalog Number: |
78567 |
other_names: | JNK3;JNK3A;PRKM10;SAPK1b;p493F12;p54bSAPK;MAPK10 |
Amount: |
100μg |
calculated_mw: | 53kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P53779 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human JNK3 |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015] |
References: |
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appl_detail: |
WB 1:500 - 1:2000 |
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