NEDD4 Rabbit mAb

Catalog Number:

78545

Amount:

100μg

Price:

$318

Swiss-Prot No:

P46934

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human NEDD4

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF