EAAT2/SLC1A2 Rabbit mAb

Catalog Number:

78530

Amount:

100μg

Price:

$318

Swiss-Prot No:

P43004

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human EAAT2/SLC1A2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF