α-Actin-1 (ACTA1) Rabbit mAb

Catalog Number:

78521

Amount:

100μg

Price:

$318

Swiss-Prot No:

P68133

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human α-Actin-1 (ACTA1)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF