TLR5 Rabbit mAb

Catalog Number:

78516

Amount:

100μg

Price:

$318

Swiss-Prot No:

O60602

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human TLR5

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF