SDHB Rabbit mAb

Catalog Number:

78514

Amount:

100μg

Price:

$318

Swiss-Prot No:

P21912

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human SDHB

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF